Further Good News from Prophylactic Human Papillomavirus Vaccines: Long-Term Duration of Immunity
نویسندگان
چکیده
منابع مشابه
Prophylactic human papillomavirus vaccines.
Human papillomavirus (HPV) infection causes virtually all cases of cervical cancer, the second most common cause of death from cancer among women worldwide. This Review examines prophylactic HPV subunit vaccines based on the ability of the viral L1 capsid protein to form virus-like particles (VLPs) that induce high levels of neutralizing antibodies. Following preclinical research by laboratorie...
متن کاملProphylactic immunization with human papillomavirus vaccines induces oral immunity in mice.
OBJECTIVE Although it has been shown that prophylactic vaccination can induce genital immunity, there is inadequate information on human papillomavirus (HPV) vaccine-induced oral immunity, which is of particular interest due to HPV-associated oropharyngeal malignancies and recurrent respiratory papillomatosis. Therefore, we assessed the efficacy of various HPV vaccines against oral HPV pseudovi...
متن کاملHuman Papillomavirus Prophylactic Vaccines and Alternative Strategies for Prevention
First evidence that transmissible agents are involved in the development of cervical cancer dates back to the mid 19th century and is based on investigations of the Italian physi‐ cian Demonico Rigoni-Stern who recognized that cancer of the womb is found most frequently among women in their fourth and fifth decade and that factors such as age of sexual debut and promiscuity attribute to the ris...
متن کاملHuman papillomavirus-associated cervical cancer: Prophylactic and therapeutic vaccines
Abbreviations: Adeno-associated virus, (AAV); bacilli Calmette-Guerin, (BCG); base pairs, (bp); cottontail rabbit papilloma virus, (CRPV); E6-associated protein, (E6-AP); epidermal growth factor receptor, (EGFR); histone deacetylases, (HDAC); human papillomavirus, (HPV); inverted terminal repeats, (ITRs); listerolysin O, (LLO); of lysosome-associated membrane protein, (LAMP); open reading frame...
متن کاملDevelopment and implementation of papillomavirus prophylactic vaccines.
Translation of basic scientific findings into practical patient outcomes is a significant exercise even when the goal is conceptually straightforward, as in the development of a vaccine for an infectious disease. Recognition of the association of cervical cancer with papillomavirus infection encouraged development of a vaccine to help with prevention of this very common cancer, causing over 250...
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ژورنال
عنوان ژورنال: Women's Health
سال: 2010
ISSN: 1745-5065,1745-5065
DOI: 10.2217/whe.10.18